A process optimization for bio-catalytic production of substituted catechols (3-nitrocatechol and 3-methylcatechol

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A process optimization for bio-catalytic production of substituted catechols (3-nitrocatechol and 3-methylcatechol

BACKGROUND Substituted catechols are important precursors for large-scale synthesis of pharmaceuticals and other industrial products. Most of the reported chemical synthesis methods are expensive and insufficient at industrial level. However, biological processes for production of substituted catechols could be highly selective and suitable for industrial purposes. RESULTS We have optimized a...

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Simultaneous Optimization of Production and Quality in a Deterioration Process

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Simultaneous Optimization of Production and Quality in a Deterioration Process

Achieving optimal production cycle time for improving manufacturing processes is one of the common problems in production planning. During recent years, different approaches have been developed for solving this problem, but most of them assume that mean quality characteristic is constant over production run length and sets it on customer’s target value. However, the process mean may drift from ...

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ژورنال

عنوان ژورنال: BMC Biotechnology

سال: 2010

ISSN: 1472-6750

DOI: 10.1186/1472-6750-10-49